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POWERLAB INC scope application software
Scope Application Software, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/scope+software/scope+software/pmc12079604-125-17-8
Average 90 stars, based on 1 article reviews
scope application software - by Bioz Stars, 2026-09
90/100 stars

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Article Title: DFO treatment protects against depression-like behaviors and cognitive impairment in CUMS mice.
Article Snippet: Depression has several negative effects on emotion as well as learning and memory abilities.. Previous studies showed that depression could exacerbate inflammation, which in turn further aggravated depression.. Deferoxamine (DFO) is a chelating agent binding iron and aluminium, and is clinically applied to treat acute ion poisoning and hemochromatosis.

Article Title: Insulin-induced long-term potentiation in the dentate gyrus of hippocampal formation.
Article Snippet: The discovery that brain areas involving in learning and memory express receptors for insulin hormone, led to the idea that insulin signaling may have a role in regulating cognitive function.. Although previous studies have shown a role for insulin in regulation of the threshold of plasticity induction, no study has addressed whether insulin can induce a chemical plasticity per se.. Young-adult male rats that are fed with standard diets with or without carbohydrate syrup (sucrose or high-fructose corn syrups) were enrolled in this study.

Article Title: FSTL1-knockdown improves neural oscillation via decreasing neuronal-inflammation regulating apoptosis in Aβ 1-42 induced AD model mice.
Article Snippet: Follistatin like protein 1 (FSTL1) is a famous growth regulatory protein.. FSTL1 has been noticed in many diseases, including heart and lung ischemia, cerebral ischemia, glioma, schizophrenia, and Autism.. The role of FSTL1 has been declared in the genetics and development of the central nervous system.

Article Title: Legumain knockout improves repeated corticosterone injection-induced depression-like emotional and cognitive deficits.
Article Snippet: Emotional and cognitive impairment has been recognized as a central feature of depression, which is closely related to hyperfunction of the hypothalamic-pituitary-adrenal (HPA) axis caused by down-regulation of glucocorticoid receptor (GR) expression in patients.. A decrease in GR expression can cause pathological changes and lead to the impairment of synaptic plasticity.. Legumain, a lysosomal cysteine protease, plays an important role in neurological diseases.

Article Title: Inhibition of Rho-kinase by fasudil contributes to the modulation of the synaptic plasticity response in the rat hippocampus.
Article Snippet: .. We recorded the field potentials composed of a positive excitatory postsynaptic potential (fEPSP) and a negative population spike (PS) from the DG, digitized at a sampling rate of 40 kHz, and stored them on a computer for later analyses using SCOPE software (PowerLab ADInstruments, version 3.6.10). ..

Sampling:

Article Title: Insulin-induced long-term potentiation in the dentate gyrus of hippocampal formation.
Article Snippet: The discovery that brain areas involving in learning and memory express receptors for insulin hormone, led to the idea that insulin signaling may have a role in regulating cognitive function.. Although previous studies have shown a role for insulin in regulation of the threshold of plasticity induction, no study has addressed whether insulin can induce a chemical plasticity per se.. Young-adult male rats that are fed with standard diets with or without carbohydrate syrup (sucrose or high-fructose corn syrups) were enrolled in this study.

Article Title: Inhibition of Rho-kinase by fasudil contributes to the modulation of the synaptic plasticity response in the rat hippocampus.
Article Snippet: .. We recorded the field potentials composed of a positive excitatory postsynaptic potential (fEPSP) and a negative population spike (PS) from the DG, digitized at a sampling rate of 40 kHz, and stored them on a computer for later analyses using SCOPE software (PowerLab ADInstruments, version 3.6.10). ..

other:

Article Title: VPA-induced autism impairs memory ability through disturbing neural oscillatory patterns in offspring rats.
Article Snippet: Autism spectrum disorder (ASD) is a general neurodevelopmental disease characterized by unusual social communication and rigid, repetitive behavior patterns.. The purpose of this study was to investigate the effects of ASD on the alteration of neural oscillatory patterns and synaptic plasticity, which commonly supported a wide range of basic and higher memory activities.. Accordingly, a prenatal valproic acid (VPA) exposure rat model was established for studying autism.

Article Title: Prelimbic proBDNF Facilitates Retrieval-Dependent Fear Memory Destabilization by Regulation of Synaptic and Neural Functions in Juvenile Rats.
Article Snippet: Fear regulation changes as a function of the early life is a key developmental period for the continued maturation of fear neural circuitry.. The mechanisms of fear retrieval-induced reconsolidation have been investigated but remain poorly understood.. The involvement of prelimbic proBDNF in fear memory extinction and its mediated signaling have been reported previously.

Article Title: MST1 ‐knockdown protects against impairment of working memory via regulating neural activity in depression‐like mice
Article Snippet: Firstly, a stimulative optimal intensity that could evoke 70% response of its maximum amplitude (range 0.3–0.5 mA) was delivered at single‐pulse stimulation to record a 20‐min baseline (Scope software, PowerLab).



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